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PDCD1LG2 抗体 (AA 31-80)

The 兔 多克隆 anti-PDCD1LG2 antibody is suitable to detect PDCD1LG2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN8123955
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PDCD1LG2 抗体 (AA 31-80) (ABIN8123955)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

适用

  • 130
  • 34
  • 10
  • 3
人, 小鼠, 大鼠

宿主

  • 70
  • 64
  • 20
  • 1
兔

克隆类型

  • 103
  • 49
  • 2
多克隆

标记

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  • 2
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This PDCD1LG2 antibody is un-conjugated

应用范围

  • 83
  • 70
  • 37
  • 33
  • 27
  • 13
  • 8
  • 5
  • 5
  • 5
  • 4
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 29
    • 21
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    • 2
    • 2
    • 1
    • 1
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    AA 31-80

    原理

    PD-L2 Antibody

    特异性

    The antibody detects endogenous PD-L2

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic peptide from human protein at AA range: 31-80

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    PD-L2

    背景

    Synonyms: Programmed cell death 1 ligand 2 (PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD antigen CD273)

    Background: function:Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.,induction:Up-regulated by IFNG stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4.,similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with PDCD1.,tissue specificity:Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.,

    Gene Name: PDCD1LG2 B7DC CD273 PDCD1L2 PDL2

    Protein Name: Programmed cell death 1 ligand 2 (PD-1 ligand 2) (PD-L2) (PDCD1 ligand 2) (Programmed death ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD antigen CD273)

    基因ID

    80380

    UniProt

    Q9BQ51
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