PHC3 抗体 (AA 720-800)
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北京 101111
Quick Overview for PHC3 抗体 (AA 720-800) (ABIN8123853)
抗原
See all PHC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 720-800
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原理
- PHC3 Antibody
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特异性
- PHC3 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 720-800
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亚型
- IgG
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anti-Polyhomeotic Homolog 3 (PHC3) (AA 819-850) antibody
PHC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB54120 unconjugated
anti-Polyhomeotic Homolog 3 (PHC3) antibodyPHC3 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Polyhomeotic Homolog 3 (PHC3) (AA 700-750) antibodyPHC3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Polyhomeotic Homolog 3 (PHC3) (AA 100-300) antibodyPHC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PHC3 (Polyhomeotic Homolog 3 (PHC3))
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别名
- PHC3
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背景
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Background: function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2.,
Gene Name: PHC3 EDR3 PH3
Protein Name: Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)
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基因ID
- 80012
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UniProt
- Q8NDX5
抗原
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