电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PAOX 抗体 (AA 260-340)

The 兔 多克隆 anti-PAOX antibody (ABIN8123848) specifically detects PAOX in WB, ELISA, IHC 和 IF. The antibody is reactive with 小鼠, 人 和 大鼠 samples.
产品编号 ABIN8123848
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PAOX 抗体 (AA 260-340) (ABIN8123848)

抗原

See all PAOX 抗体
PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

适用

  • 22
  • 21
  • 10
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
小鼠, 人, 大鼠

宿主

  • 27
  • 1
兔

克隆类型

  • 28
多克隆

标记

  • 19
  • 3
  • 2
  • 2
  • 1
  • 1
This PAOX antibody is un-conjugated

应用范围

  • 22
  • 15
  • 10
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-340

    原理

    PAOX Antibody

    特异性

    PAOX Polyclonal Antibody detects endogenous levels of PAOX protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from PAOX . at AA range: 260-340

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

    别名

    PAOX

    背景

    Synonyms: PAOX, PAO, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase

    Background: catalytic activity:N(1),N(12)-diacetylspermine + O(2) + H(2)O = N(1)-acetylspermidine + 3-acetamidobutanal + H(2)O(2).,catalytic activity:N(1)-acetylspermidine + O(2) + H(2)O = putrescine + 3-acetamidopropanal + H(2)O(2).,catalytic activity:N(1)-acetylspermine + O(2) + H(2)O = spermidine + 3-acetamidopropanal + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,function:Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.,induction:By polyamine analogs.,miscellaneous:Oxidizes N(1)-acetylated polyamines on the exo-side of their N(4)-amino groups. Plant PAO oxidizes spermine on the endo-side of the N(4)-nitrogen.,pathway:Amine and polyamine metabolism, spermine metabolism.,similarity:Belongs to the flavin monoamine oxidase family.,subunit:Monomer.,tissue specificity:Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.,

    Gene Name: PAOX

    Protein Name: Peroxisomal N(1)-acetyl-spermine/spermidine oxidase

    基因ID

    196743

    UniProt

    Q6QHF9
You are here: