PDE3A 抗体 (pSer312)
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Quick Overview for PDE3A 抗体 (pSer312) (ABIN8123720)
抗原
See all PDE3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer312
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原理
- PDE3A (Phospho Ser312) Antibody
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特异性
- This antibody detects endogenous levels of PDE3A (Phospho-Ser312) at Human, Mouse,Rat
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human PDE3A (Phospho-Ser312)
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))
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别名
- PDE3A
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背景
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Synonyms: cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)
Background: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
Gene Name: PDE3A
Protein Name: PDE3A (Phospho-Ser312)
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基因ID
- 5139
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UniProt
- Q14432
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途径
- cAMP Metabolic Process
抗原
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