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P-Cadherin 抗体

The 小鼠 单克隆 anti-P-Cadherin antibody is suitable to detect P-Cadherin in samples from 人. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN8123547
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for P-Cadherin 抗体 (ABIN8123547)

抗原

See all P-Cadherin (CDH3) 抗体
P-Cadherin (CDH3)

适用

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人

宿主

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小鼠

克隆类型

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单克隆

标记

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This P-Cadherin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

AB1019
  • 原理

    P-cadherin mouse mAb

    特异性

    This antibody detects endogenous levels of P-cadherin protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 450-550 of the human P-cadherin protein.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IHC-P, 1:50-1:200 | IF, 1:100-400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    P-Cadherin (CDH3)

    别名

    P-cadherin

    背景

    Synonyms: Cadherin-3 (Placental cadherin) (P-cadherin)

    Background: cadherin 3(CDH3) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

    Gene Name: CADH3

    Protein Name: P-cadherin

    基因ID

    1001

    UniProt

    P22223
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