P-Cadherin 抗体
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北京 101111
Quick Overview for P-Cadherin 抗体 (ABIN8123547)
抗原
See all P-Cadherin (CDH3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- P-cadherin mouse mAb
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特异性
- This antibody detects endogenous levels of P-cadherin protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 450-550 of the human P-cadherin protein.
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亚型
- IgG
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应用备注
- WB, 1:500-1:2000 | IHC-P, 1:50-1:200 | IF, 1:100-400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- P-Cadherin (CDH3)
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别名
- P-cadherin
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背景
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Synonyms: Cadherin-3 (Placental cadherin) (P-cadherin)
Background: cadherin 3(CDH3) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],
Gene Name: CADH3
Protein Name: P-cadherin
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基因ID
- 1001
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UniProt
- P22223
抗原
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