P-Cadherin 抗体
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北京 101111
Quick Overview for P-Cadherin 抗体 (ABIN8123546)
抗原
See all P-Cadherin (CDH3) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CDH3 Antibody
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特异性
- This antibody detects endogenous levels of CDH3.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human CDH3 Polyclonal
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亚型
- IgG
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应用备注
- WB 1:500-2000, ELISA 1:10000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- P-Cadherin (CDH3)
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别名
- CDH3
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背景
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Synonyms: Cadherin-3 (Placental cadherin) (P-cadherin)
Background: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],
Gene Name: CDH3 CDHP
Protein Name: Cadherin-3 (Placental cadherin) (P-cadherin)
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基因ID
- 1001
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UniProt
- P22223
抗原
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