NCOA1 抗体 (pThr1179)
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Quick Overview for NCOA1 抗体 (pThr1179) (ABIN8123422)
抗原
See all NCOA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr1179
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原理
- SRC-1 (Phospho Thr1179) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse SRC-1 (Phospho Thr1179)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human SRC-1 (Phospho Thr1179)
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亚型
- IgG
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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别名
- SRC-1
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背景
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Synonyms: Nuclear receptor coactivator 1 (NCoA-1, EC 2.3.1.48, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1, SRC-1)
Background: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Gene Name: NCOA1 BHLHE74 SRC1
Protein Name: SRC-1 (Phospho Thr1179)
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基因ID
- 8648
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UniProt
- Q15788
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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