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NPLOC4 抗体 (AA 270-350)

This 兔 多克隆 antibody specifically detects NPLOC4 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8123420
发货至: 中国
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Quick Overview for NPLOC4 抗体 (AA 270-350) (ABIN8123420)

抗原

See all NPLOC4 抗体
NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

适用

  • 33
  • 18
  • 16
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33
  • 2
兔

克隆类型

  • 35
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This NPLOC4 antibody is un-conjugated

应用范围

  • 32
  • 23
  • 14
  • 10
  • 4
  • 4
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 12
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 270-350

    原理

    NPL4 Antibody

    特异性

    NPL4 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 270-350

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

    别名

    NPL4

    背景

    Background: domain:Binds ubiquitinated proteins via its RanBP2-type zinc finger.,function:The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.,pathway:Protein degradation, proteasomal ubiquitin-dependent pathway.,similarity:Belongs to the NPL4 family.,similarity:Contains 1 RanBP2-type zinc finger.,subcellular location:Associated with the endoplasmic reticulum and nuclear.,subunit:Heterodimer with UFD1L. The heterodimer binds ubiquitinated proteins. The heterodimer binds to VCP and inhibits Golgi membrane fusion.,tissue specificity:Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver.,

    Gene Name: NPLOC4 KIAA1499 NPL4

    Protein Name: Nuclear protein localization protein 4 homolog (Protein NPL4)

    基因ID

    55666

    UniProt

    Q8TAT6
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