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MPRIP 抗体

This 兔 多克隆 antibody specifically detects MPRIP in WB, IHC 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8123153
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MPRIP 抗体 (ABIN8123153)

抗原

See all MPRIP 抗体
MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

适用

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人, 小鼠, 大鼠

宿主

  • 34
  • 3
兔

克隆类型

  • 32
  • 5
多克隆

标记

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This MPRIP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 原理

    M-RIP Antibody

    特异性

    M-RIP Polyclonal Antibody detects endogenous levels of M-RIP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human M-RIP.

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

    别名

    M-RIP

    背景

    Synonyms: MPRIP, KIAA0864, MRIP, RHOIP3, Myosin phosphatase Rho-interacting protein, M-RIP, Rho-interacting protein 3, RIP3, p116Rip

    Background: function:Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.,similarity:Contains 1 PH domain.,similarity:Contains 2 PH domains.,subcellular location:Colocalizes with F-actin.,subunit:Binds F-actin through its N-terminus (By similarity). Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains.,

    Gene Name: MPRIP

    Protein Name: Myosin phosphatase Rho-interacting protein

    基因ID

    23164

    UniProt

    Q6WCQ1
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