MLKL 抗体 (pSer358)
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北京 101111
Quick Overview for MLKL 抗体 (pSer358) (ABIN8123028)
抗原
See all MLKL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer358
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原理
- MLKL (phospho Ser358) Antibody
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特异性
- This antibody detects endogenous phospho levels of MLKL (phospho S358) at Human, Mouse, Rat
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human MLKL (phospho S358)
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亚型
- IgG
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anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibody
MLKL 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer347) antibodyMLKL 适用: 人, 小鼠 IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2935 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4615 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4620 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2895 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) (Internal Region) antibodyMLKL 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibodyMLKL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer358) antibodyMLKL 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal 6E3 unconjugated
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应用备注
- IHC 1:100-500,IF ICC 1:100-500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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别名
- MLKL
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背景
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Synonyms: Mixed lineage kinase domain-like protein
Background: This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain, however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015],
Gene Name: MLKL
Protein Name: MLKL (phospho S358)
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基因ID
- 197259
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UniProt
- Q8NB16
抗原
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