MARCH1 抗体
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北京 101111
Quick Overview for MARCH1 抗体 (ABIN8122860)
抗原
See all MARCH1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MARCH1 Antibody
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特异性
- MARCH1 Polyclonal Antibody detects endogenous levels of 40603 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human 40603.
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亚型
- IgG
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anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (AA 36-85) antibody
MARCH1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (C-Term) antibodyMARCH1 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (AA 1-99) antibodyMARCH1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (AA 1-99) antibodyMARCH1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1) (Center) antibodyMARCH1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
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别名
- MARCH1
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背景
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Synonyms: MARCH1, RNF171, E3 ubiquitin-protein ligase MARCH1, Membrane-associated RING finger protein 1, Membrane-associated RING-CH protein I, MARCH-I, RING finger protein 171
Background: MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266], Thibodeau et al., 2008 [PubMed 18389477], De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010],
Gene Name: MARCH1
Protein Name: E3 ubiquitin-protein ligase MARCH1
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基因ID
- 55016
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UniProt
- Q8TCQ1
抗原
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