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MED1 抗体 (AA 650-750)

The 小鼠 单克隆 anti-MED1 antibody is suitable to detect MED1 in samples from 人. It has been validated for WB, ELISA 和 IF.
产品编号 ABIN8122821
发货至: 中国
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Quick Overview for MED1 抗体 (AA 650-750) (ABIN8122821)

抗原

See all MED1 抗体
MED1 (Mediator Complex Subunit 1 (MED1))

适用

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人

宿主

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小鼠

克隆类型

  • 51
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单克隆

标记

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This MED1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

AB2369
  • 抗原表位

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    AA 650-750

    原理

    MED1 mouse mAb

    特异性

    This antibody detects endogenous levels of MED1 protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 650 - 750 of the human MED1 protein.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    MED1 (Mediator Complex Subunit 1 (MED1))

    别名

    MED1

    背景

    Synonyms: MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2

    Background: mediator complex subunit 1 (MED1) Homo sapiens The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e. g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008],

    Gene Name: Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome prolifeRator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)

    Protein Name: MED1

    基因ID

    5469

    UniProt

    Q15648

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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