MMP8 抗体 (Cleaved-Leu101)
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北京 101111
Quick Overview for MMP8 抗体 (Cleaved-Leu101) (ABIN8122805)
抗原
See all MMP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Leu101
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原理
- MMP8 (Cleaved-Leu101) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse,Rat MMP8 (Cleaved-Leu101, protein was cleaved amino acid sequence between 100-101 )
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human MMP8 (Cleaved-Leu101)
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亚型
- IgG
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anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) antibody
MMP8 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 101-467) antibodyMMP8 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) antibodyMMP8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 241-340) antibodyMMP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (N-Term) antibodyMMP8 适用: 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 286-315) antibodyMMP8 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2017-2018 unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 101-467) antibodyMMP8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 22-283) antibodyMMP8 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 1-467) antibodyMMP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 1-467) antibodyMMP8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
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别名
- MMP8
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背景
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Synonyms: Neutrophil collagenase (EC 3.4.24.34, Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL)
Background: catalytic activity:Cleavage of interstitial collagens in the triple helical domain. Unlike EC 3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 3 calcium ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,enzyme regulation:Cannot be activated without removal of the activation peptide.,function:Can degrade fibrillar type I, II, and III collagens.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,subcellular location:Stored in intracellular granules.,tissue specificity:Neutrophils.,
Gene Name: MMP8 CLG1
Protein Name: MMP8 (Cleaved-Leu101)
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基因ID
- 4317
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UniProt
- P22894
抗原
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