MMP13 抗体 (Cleaved-Tyr104)
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北京 101111
Quick Overview for MMP13 抗体 (Cleaved-Tyr104) (ABIN8122795)
抗原
See all MMP13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Tyr104
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原理
- MMP13 (Cleaved-Tyr104) Antibody
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特异性
- This antibody detects endogenous levels of Human MMP13 (Cleaved-Tyr104, protein was cleaved amino acid sequence between 103-104 )
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human MMP13 (Cleaved-Tyr104)
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亚型
- IgG
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anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 201-300) antibody
MMP13 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 103-290) antibodyMMP13 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) antibodyMMP13 适用: 人 WB, IHC, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 290-468) antibodyMMP13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 362-471) antibodyMMP13 适用: 人 WB, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 3B11 unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 99-335) antibodyMMP13 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 295-324), (C-Term) antibodyMMP13 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2094 unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 253-282) antibodyMMP13 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB33646 unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) antibodyMMP13 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 70-245) antibody (APC)MMP13 适用: 兔 ICC, IF 宿主: 豚鼠 Polyclonal APC
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
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别名
- MMP13
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背景
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Synonyms: Collagenase 3 (EC 3.4.24.-, Matrix metalloproteinase-13, MMP-13)
Background: cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 4 calcium ions per subunit.,disease:Defects in MMP13 are the cause of spondyloepimetaphyseal dysplasia type 2 (SEMD2) [MIM:602111], also known as spondyloepimetaphyseal dysplasia type Missouri. SEMDs are a heterogeneous group of skeletal disorders characterized by defective growth and modeling of the spine and long bones. The SEMDs are distinguished from the spondylometaphyseal dysplasias and the spondyloepiphyseal dysplasias by the combined involvement of the epiphyses and metaphyses. The 3 disorders have malformations of the vertebrae in common.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades collagen type I. Does not act on gelatin or casein. Could have a role in tumoral process.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,tissue specificity:Seems to be specific to breast carcinomas.,
Gene Name: MMP13
Protein Name: MMP13 (Cleaved-Tyr104)
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基因ID
- 4322
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UniProt
- P45452
抗原
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