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KDM3B 抗体 (AA 230-310)

This 兔 多克隆 antibody specifically detects KDM3B in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8122715
发货至: 中国
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Quick Overview for KDM3B 抗体 (AA 230-310) (ABIN8122715)

抗原

See all KDM3B 抗体
KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

适用

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人, 小鼠

宿主

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兔

克隆类型

  • 64
多克隆

标记

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This KDM3B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 230-310

    原理

    KDM3B Antibody

    特异性

    KDM3B Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 230-310

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

    别名

    KDM3B

    背景

    Background: cofactor:Binds 1 Fe(2+) ion per subunit.,domain:Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.,similarity:Belongs to the JHDM2 histone demethylase family.,similarity:Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,

    Gene Name: KDM3B C5orf7 JHDM2B JMJD1B KIAA1082

    Protein Name: Lysine-specific demethylase 3B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA)

    基因ID

    51780

    UniProt

    Q7LBC6

    途径

    Warburg Effect
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