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LY75/DEC-205 抗体

This 兔 多克隆 antibody specifically detects LY75/DEC-205 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8122700
发货至: 中国
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Quick Overview for LY75/DEC-205 抗体 (ABIN8122700)

抗原

See all LY75/DEC-205 (LY75) 抗体
LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

适用

  • 76
  • 45
  • 8
  • 8
  • 4
  • 1
人, 小鼠, 大鼠

宿主

  • 53
  • 34
  • 14
  • 6
  • 1
  • 1
兔

克隆类型

  • 71
  • 32
  • 4
多克隆

标记

  • 51
  • 10
  • 9
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
This LY75/DEC-205 antibody is un-conjugated

应用范围

  • 39
  • 31
  • 30
  • 19
  • 17
  • 16
  • 15
  • 9
  • 6
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    CD205 Antibody

    特异性

    CD205 Polyclonal Antibody detects endogenous levels of CD205 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human CD205.

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

    别名

    CD205

    背景

    Synonyms: LY75, CD205, CLEC13B, Lymphocyte antigen 75, Ly-75, C-type lectin domain family 13 member B, DEC-205, gp200-MR6, CD antigen CD205

    Background: function:Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.,miscellaneous:Isoform 2 and isoform 3 are produced in HRS cells by a transcriptional control mechanism which cotranscribe an mRNA containing LY75 and CD302 prior to generating the intergenically spliced mRNA to produce LY75/CD302 fusion proteins.,online information:DEC-205,PTM:N-glycosylated.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 ricin B-type lectin domain.,similarity:Contains 10 C-type lectin domains.,tissue specificity:Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin's lymphoma cells called Hodgkin's and Reed-Sternberg (HRS) cells.,tissue specificity:Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin's lymphoma cells called Hodgkin's and Reed-Sternberg (HRS) cells.,

    Gene Name: LY75

    Protein Name: Lymphocyte antigen 75

    基因ID

    4065

    UniProt

    O60449
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