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LDLR 抗体 (AA 540-620)

The 兔 多克隆 anti-LDLR antibody is suitable to detect LDLR in samples from 人, 小鼠, 大鼠 和 Cow. It has been validated for WB 和 ELISA.
产品编号 ABIN8122674
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LDLR 抗体 (AA 540-620) (ABIN8122674)

抗原

See all LDLR 抗体
LDLR (Low Density Lipoprotein Receptor (LDLR))

适用

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人, 小鼠, 大鼠, Cow

宿主

  • 110
  • 13
  • 3
兔

克隆类型

  • 96
  • 29
  • 1
多克隆

标记

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This LDLR antibody is un-conjugated

应用范围

  • 93
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  • 15
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Western Blotting (WB), ELISA
  • 抗原表位

    • 16
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    AA 540-620

    原理

    LDLR Antibody

    特异性

    LDLR Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 540-620

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    LDLR (Low Density Lipoprotein Receptor (LDLR))

    别名

    LDLR

    背景

    Background: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010],

    Gene Name: LDLR

    Protein Name: Low-density lipoprotein receptor (LDL receptor)

    基因ID

    3949

    UniProt

    P01130

    途径

    Hepatitis C, Lipid Metabolism
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