Lrig1 抗体
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北京 101111
Quick Overview for Lrig1 抗体 (ABIN8122633)
抗原
See all Lrig1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LRIG1 Antibody
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特异性
- LRIG1 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
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别名
- LRIG1
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背景
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Background: domain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted.,function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.,induction:By EGF.,similarity:Contains 17 LRR (leucine-rich) repeats.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4.,tissue specificity:Widely expressed.,
Gene Name: LRIG1 LIG1
Protein Name: Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1)
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基因ID
- 26018
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UniProt
- Q96JA1
抗原
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