LRWD1 抗体 (AA 395-445)
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北京 101111
Quick Overview for LRWD1 抗体 (AA 395-445) (ABIN8122629)
抗原
See all LRWD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 395-445
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原理
- LRWD1 Antibody
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特异性
- This antibody detects endogenous levels of LRWD1 at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human LRWD1 AA range: 395-445
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
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别名
- LRWD1
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背景
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Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
Gene Name: LRWD1 ORCA
Protein Name: LRWD1
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基因ID
- 222229
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UniProt
- Q9UFC0
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途径
- Chromatin Binding
抗原
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