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LINGO1 抗体 (AA 370-450)

The 兔 多克隆 anti-LINGO1 antibody (ABIN8122624) specifically detects LINGO1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8122624
发货至: 中国
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Quick Overview for LINGO1 抗体 (AA 370-450) (ABIN8122624)

抗原

See all LINGO1 抗体
LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

适用

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  • 1
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人, 小鼠

宿主

  • 73
  • 5
兔

克隆类型

  • 73
  • 5
多克隆

标记

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This LINGO1 antibody is un-conjugated

应用范围

  • 40
  • 34
  • 26
  • 14
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  • 11
  • 7
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

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    • 1
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    AA 370-450

    原理

    LIGO1 Antibody

    特异性

    LIGO1 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 370-450

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

    别名

    LIGO1

    背景

    Background: function:Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.,PTM:N-glycosylated. Contains predominantly high-mannose glycans.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Homotetramer. Forms ternary complex with RTN4R/NGFR and RTN4R/TNFRSF19.,tissue specificity:Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.,

    Gene Name: LINGO1 LERN1 LRRN6A UNQ201/PRO227

    Protein Name: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (Leucine-rich repeat and immunoglobilin domain-containing protein 1) (Leucine-rich repeat neuronal protein 1) (Leucine-rich repeat neuronal protein 6A)

    基因ID

    84894

    UniProt

    Q96FE5
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