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Leptin Receptor 抗体 (AA 791-840)

The 兔 多克隆 anti-Leptin Receptor antibody (ABIN8122621) specifically detects Leptin Receptor in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8122621
发货至: 中国
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Quick Overview for Leptin Receptor 抗体 (AA 791-840) (ABIN8122621)

抗原

See all Leptin Receptor (LEPR) 抗体
Leptin Receptor (LEPR)

适用

  • 138
  • 55
  • 30
  • 12
  • 1
人, 小鼠, 大鼠

宿主

  • 132
  • 27
  • 5
  • 1
  • 1
  • 1
兔

克隆类型

  • 123
  • 44
多克隆

标记

  • 70
  • 12
  • 10
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Leptin Receptor antibody is un-conjugated

应用范围

  • 101
  • 49
  • 48
  • 45
  • 28
  • 28
  • 22
  • 15
  • 14
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 16
    • 13
    • 12
    • 12
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 791-840

    原理

    Ob-R Antibody

    特异性

    Ob-R Polyclonal Antibody detects endogenous levels of Ob-R protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from Leptin receptor at AA range: 791-840

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Leptin Receptor (LEPR)

    别名

    Ob-R

    背景

    Synonyms: LEPR, DB, OBR, Leptin receptor, LEP-R, HuB219, OB receptor, OB-R, CD295

    Background: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010],

    Gene Name: LEPR OBR

    Protein Name: Leptin receptor

    基因ID

    3953

    UniProt

    P48357

    途径

    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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