KRT17 抗体 (AA 300-432)
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北京 101111
Quick Overview for KRT17 抗体 (AA 300-432) (ABIN8122459)
抗原
See all KRT17 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 300-432
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原理
- Cytokeratin 17 mouse mAb
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特异性
- The antibody can specifically recognize human CK17 protein. In western blotting of Hela and A431 cell lysates, the antibody can label a 46 kDa band corresponding to CK17.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 300 - 432 of the human Cytokeratin 17 protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- KRT17 (Keratin 17 (KRT17))
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别名
- Cytokeratin 17
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背景
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Synonyms: 39. 1, CK 17, CK-17, CytokeRatin-17, K17, K1C17_HUMAN, KeRatin 17, keRatin 17 epitope S1, keRatin 17 epitope S2, keRatin 17 epitope S4, KeRatin 17, type I, KeRatin, KeRatin type I cytoskeletal 17, keRatin, type i cytoskeletal 17 [version 1], KeRatin-17, KRT17, PC, PC2, PCHC1, type I cytoskeletal 17
Background: CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.
Gene Name: KRT17
Protein Name: Cytokeratin 17
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基因ID
- 3872
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UniProt
- Q04695
抗原
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