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KRT17 抗体 (AA 300-432)

The 小鼠 单克隆 anti-KRT17 antibody (Clone AB1523) (ABIN8122459) specifically detects KRT17 in WB, IHC, IF 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8122459
发货至: 中国
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Quick Overview for KRT17 抗体 (AA 300-432) (ABIN8122459)

抗原

See all KRT17 抗体
KRT17 (Keratin 17 (KRT17))

适用

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人, 大鼠, 小鼠

宿主

  • 138
  • 46
  • 1
小鼠

克隆类型

  • 99
  • 85
  • 1
单克隆

标记

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This KRT17 antibody is un-conjugated

应用范围

  • 129
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

克隆位点

AB1523
  • 抗原表位

    • 17
    • 15
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    AA 300-432

    原理

    Cytokeratin 17 mouse mAb

    特异性

    The antibody can specifically recognize human CK17 protein. In western blotting of Hela and A431 cell lysates, the antibody can label a 46 kDa band corresponding to CK17.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 300 - 432 of the human Cytokeratin 17 protein.

    亚型

    IgG
  • 应用备注

    IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    KRT17 (Keratin 17 (KRT17))

    别名

    Cytokeratin 17

    背景

    Synonyms: 39. 1, CK 17, CK-17, CytokeRatin-17, K17, K1C17_HUMAN, KeRatin 17, keRatin 17 epitope S1, keRatin 17 epitope S2, keRatin 17 epitope S4, KeRatin 17, type I, KeRatin, KeRatin type I cytoskeletal 17, keRatin, type i cytoskeletal 17 [version 1], KeRatin-17, KRT17, PC, PC2, PCHC1, type I cytoskeletal 17

    Background: CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.

    Gene Name: KRT17

    Protein Name: Cytokeratin 17

    基因ID

    3872

    UniProt

    Q04695
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