Cytokeratin 13 抗体 (AA 400-458)
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北京 101111
Quick Overview for Cytokeratin 13 抗体 (AA 400-458) (ABIN8122439)
抗原
See all Cytokeratin 13 (KRT13) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 400-458
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原理
- Cytokeratin 13 mouse mAb
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特异性
- The antibody can specifically recognize human CK13 protein. In western blotting of A431 cell lysate, the antibody can label a 50 kDa band corresponding to CK13.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 400 - 458 of the human Cytokeratin 13 protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
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别名
- Cytokeratin 13
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背景
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Synonyms: 47 kDa cytokeRatin, CK-13, CK13, Cytokeratin 13, CytokeRatin-13, K13, K1C13_HUMAN, Ka13, KeRatin 13, KeRatin, keRatin type I cytoskeletal 13, KeRatin-13, Krt-1. 13, Krt1-13, KRT13, MGC161462, MGC3781, type I cytoskeletal 13, Type I keRatin Ka13, WSN2
Background: Cytokeratin 13 (CK13) is a 54 kDa protein which belongs to the intermediate filament family. CK13 protein is highly expressed in normal tissues and gradually decreased or disappeared in malignant tissues. Defects in the CK13 gene may lead to white sponge nevus of cannon (WSN) , a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia. CK13 can be used as an auxiliary indicator in the diagnosis of precancerous lesions.
Gene Name: KRT13
Protein Name: Cytokeratin 13
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基因ID
- 3860
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UniProt
- P13646
抗原
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