KEAP1 抗体 (AA 400-500)
Our Local Distributor
北京 101111
Quick Overview for KEAP1 抗体 (AA 400-500) (ABIN8122422)
抗原
See all KEAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 400-500
-
原理
- Keap1 mouse mAb
-
特异性
- This antibody detects endogenous levels of Keap1 protein.
-
纯化方法
- The antibody was purified by protein G affinity chromatography.
-
免疫原
- A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Keap1 protein.
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
-
别名
- Keap1
-
背景
-
Synonyms: Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, Kelch-like protein 19, KEAP1, INRF2
Background: kelch like ECH associated protein 1 (KEAP1) Homo sapiens This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: KEAP1
Protein Name: Keap1
-
基因ID
- 9817
-
UniProt
- Q14145
-
途径
- Maintenance of Protein Location
抗原
-