KPNA6 抗体 (AA 404-454)
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北京 101111
Quick Overview for KPNA6 抗体 (AA 404-454) (ABIN8122417)
抗原
See all KPNA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 404-454
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原理
- KPNA6 Antibody
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特异性
- This antibody detects endogenous levels of KPNA6 at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human KPNA6 AA range: 404-454
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
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别名
- KPNA6
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背景
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Synonyms: Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.The protein encoded byThis gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],
Gene Name: KPNA6 IPOA7
Protein Name: KPNA6
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基因ID
- 23633
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UniProt
- O60684
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途径
- Protein targeting to Nucleus
抗原
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