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IL-15 抗体 (AA 111-160)

The 兔 多克隆 anti-IL-15 antibody (ABIN8122321) specifically detects IL-15 in IHC, ELISA 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8122321
发货至: 中国
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Quick Overview for IL-15 抗体 (AA 111-160) (ABIN8122321)

抗原

See all IL-15 (IL15) 抗体
IL-15 (IL15) (Interleukin 15 (IL15))

适用

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人, 大鼠, 小鼠

宿主

  • 112
  • 60
  • 7
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兔

克隆类型

  • 111
  • 75
多克隆

标记

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This IL-15 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 53
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    AA 111-160

    原理

    IL-15 Antibody

    特异性

    The antibody detects endogenous IL-15

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic peptide from human protein at AA range: 111-160

    亚型

    IgG
  • 应用备注

    IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    IL-15 (IL15) (Interleukin 15 (IL15))

    别名

    IL-15

    背景

    Synonyms: Interleukin-15 (IL-15)

    Background: The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb

    Gene Name: IL15

    Protein Name: Interleukin-15 (IL-15)

    基因ID

    3600

    UniProt

    P40933

    途径

    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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