IL12B 抗体 (AA 241-290)
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北京 101111
Quick Overview for IL12B 抗体 (AA 241-290) (ABIN8122319)
抗原
See all IL12B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 241-290
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原理
- IL-12B p40 Antibody
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特异性
- The antibody detects endogenous IL-12B p40
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic peptide from human protein at AA range: 241-290
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亚型
- IgG
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anti-Interleukin 12 beta (IL12B) (AA 201-300) antibody
IL12B 适用: 人, 小鼠 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 264-290), (C-Term) antibodyIL12B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28444 unconjugated
anti-Interleukin 12 beta (IL12B) (C-Term) antibodyIL12B 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-328) antibodyIL12B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-327) antibodyIL12B 适用: 绵羊 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 30-320) antibodyIL12B 适用: 人 IHC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 12 beta (IL12B) (AA 229-328) antibodyIL12B 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Interleukin 12 beta (IL12B) (C-Term) antibodyIL12B 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal AFfirm8267 unconjugated
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应用备注
- WB 1:500-2000,IHC 1:500-200, ELISA 1:10000-20000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL12B (Interleukin 12 beta (IL12B))
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别名
- IL-12B p40
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背景
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Synonyms: Interleukin-12 subunit beta (IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, NK cell stimulatory factor chain 2, NKSF2)
Background: This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provi
Gene Name: IL12B NKSF2
Protein Name: Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2)
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基因ID
- 3593
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UniProt
- P29460
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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