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IRF4 抗体 (AA 350-451)

The 小鼠 单克隆 anti-IRF4 antibody is suitable to detect IRF4 in samples from 人. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN8122293
发货至: 中国
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Quick Overview for IRF4 抗体 (AA 350-451) (ABIN8122293)

抗原

See all IRF4 抗体
IRF4 (Interferon Regulatory Factor 4 (IRF4))

适用

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人

宿主

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小鼠

克隆类型

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单克隆

标记

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This IRF4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

AB1262
  • 抗原表位

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    AA 350-451

    原理

    IRF-4/MUM1 mouse mAb

    特异性

    The antibody can specifically recognize human MUM1 protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 350 - 451 of the human IRF - 4/MUM1 protein.

    亚型

    IgG
  • 应用备注

    IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    IRF4 (Interferon Regulatory Factor 4 (IRF4))

    别名

    IRF-4/MUM1

    背景

    Synonyms: Interferon regulatory factor 4, IRF 4, IRF-4, Irf4, IRF4_HUMAN, LSIRF, Lymphocyte specific interferon regulatory factor, Lymphocyte specific IRF, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, MUM 1, MUM1, NF EM5, NF-EM5, NFEM5, PU. 1 interaction partner, Sfpi1/PU. 1 interaction partner, Transcriptional activator PIP

    Background: MUM1, also known as interferon regulatory factor 4, with a molecular weight of 50 kDa, is a nuclear transcription factor necessary for the development and activation of B lymphocytes. It can regulate the proliferation and differentiation of B cells and activate T lymphocytes. It is mainly used for the study of B-cell lymphoma. It is expressed in multiple myeloma, lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma. It can be used as a tissue derived immunophenotypic marker of B-cell lymphoma. At the same time, it is also expressed in RS cells in anaplastic large cell lymphoma, peripheral T-cell lymphoma and classical Hodgkin's lymphoma. It is an immunophenotypic marker of malignant lymphoma, only limited to lymphocytes and melanocytes.

    Gene Name: IRF4

    Protein Name: IRF-4/MUM1

    基因ID

    3662

    UniProt

    Q15306

    途径

    Chromatin Binding
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