IRF4 抗体 (AA 350-451)
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北京 101111
Quick Overview for IRF4 抗体 (AA 350-451) (ABIN8122293)
抗原
See all IRF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 350-451
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原理
- IRF-4/MUM1 mouse mAb
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特异性
- The antibody can specifically recognize human MUM1 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 350 - 451 of the human IRF - 4/MUM1 protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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别名
- IRF-4/MUM1
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背景
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Synonyms: Interferon regulatory factor 4, IRF 4, IRF-4, Irf4, IRF4_HUMAN, LSIRF, Lymphocyte specific interferon regulatory factor, Lymphocyte specific IRF, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, MUM 1, MUM1, NF EM5, NF-EM5, NFEM5, PU. 1 interaction partner, Sfpi1/PU. 1 interaction partner, Transcriptional activator PIP
Background: MUM1, also known as interferon regulatory factor 4, with a molecular weight of 50 kDa, is a nuclear transcription factor necessary for the development and activation of B lymphocytes. It can regulate the proliferation and differentiation of B cells and activate T lymphocytes. It is mainly used for the study of B-cell lymphoma. It is expressed in multiple myeloma, lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma. It can be used as a tissue derived immunophenotypic marker of B-cell lymphoma. At the same time, it is also expressed in RS cells in anaplastic large cell lymphoma, peripheral T-cell lymphoma and classical Hodgkin's lymphoma. It is an immunophenotypic marker of malignant lymphoma, only limited to lymphocytes and melanocytes.
Gene Name: IRF4
Protein Name: IRF-4/MUM1
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基因ID
- 3662
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UniProt
- Q15306
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途径
- Chromatin Binding
抗原
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