ISR-beta 抗体
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北京 101111
Quick Overview for ISR-beta 抗体 (ABIN8122223)
抗原
See all ISR-beta 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Insulin Receptor β Rabbit mAb
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特异性
- This antibody detects endogenous levels of Insulin Receptor β protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- ISR-beta (Insulin Receptor beta (ISR-beta))
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别名
- Insulin Receptor beta
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背景
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Synonyms: Insulin receptor, IR, CD antigen CD220, [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta]
Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Gene Name: INSR
Protein Name: Insulin Receptor β
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基因ID
- 3643
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UniProt
- P06213
抗原
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