ISR-beta 抗体 (pTyr1345)
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Quick Overview for ISR-beta 抗体 (pTyr1345) (ABIN8122222)
抗原
See all ISR-beta 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1345
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原理
- Insulin Receptor β (Phospho Tyr1345) Antibody
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特异性
- This antibody detects endogenous levels of Human Insulin Receptor β (phospho-Tyr1345)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human Insulin Receptor beta (Tyr1345)
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亚型
- IgG
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ISR-beta (Insulin Receptor beta (ISR-beta))
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别名
- Insulin Receptor beta
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背景
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Synonyms: Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta]
Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Gene Name: INSR
Protein Name: Insulin Receptor β (Tyr1345)
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基因ID
- 3643
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UniProt
- P06213
抗原
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