INPPL1 抗体 (pTyr1135)
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北京 101111
Quick Overview for INPPL1 抗体 (pTyr1135) (ABIN8122201)
抗原
See all INPPL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1135
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原理
- SHIP2 (Phospho Tyr1135) Antibody
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特异性
- This antibody detects endogenous levels of Human SHIP2 (phospho-Tyr1135)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human SHIP2 (Tyr1135)
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亚型
- IgG
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应用备注
- WB 1:500-2000, IF ICC 1:50-200,ELISA 1:2000-20000,IHC 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
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别名
- SHIP2
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背景
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Synonyms: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)
Background: The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq, Jan 2009],
Gene Name: INPPL1 SHIP2
Protein Name: SHIP2 (Tyr1135)
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基因ID
- 3636
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UniProt
- O15357
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途径
- Platelet-derived growth Factor Receptor Signaling
抗原
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