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ING3 抗体

This 兔 多克隆 antibody specifically detects ING3 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8122187
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ING3 抗体 (ABIN8122187)

抗原

See all ING3 抗体
ING3 (Inhibitor of Growth Family, Member 3 (ING3))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 44
  • 4
  • 2
兔

克隆类型

  • 46
  • 4
多克隆

标记

  • 29
  • 3
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  • 1
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This ING3 antibody is un-conjugated

应用范围

  • 28
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  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    ING3 Antibody

    特异性

    ING3 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ING3 (Inhibitor of Growth Family, Member 3 (ING3))

    别名

    ING3

    背景

    Background: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008],

    Gene Name: ING3 HSPC301

    Protein Name: Inhibitor of growth protein 3 (p47ING3)

    基因ID

    54556

    UniProt

    Q9NXR8
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