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Importin 5 抗体

The 兔 多克隆 anti-Importin 5 antibody (ABIN8122168) specifically detects Importin 5 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8122168
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Importin 5 抗体 (ABIN8122168)

抗原

See all Importin 5 (IPO5) 抗体
Importin 5 (IPO5)

适用

  • 35
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 31
  • 4
兔

克隆类型

  • 33
  • 2
多克隆

标记

  • 14
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Importin 5 antibody is un-conjugated

应用范围

  • 13
  • 13
  • 12
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    IPO5 Antibody

    特异性

    IPO5 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Importin 5 (IPO5)

    别名

    IPO5

    背景

    Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex.The protein encoded by this gene is a me

    Gene Name: IPO5 KPNB3 RANBP5

    Protein Name: Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)

    基因ID

    3843

    UniProt

    O00410

    途径

    Protein targeting to Nucleus
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