Importin 5 抗体
Our Local Distributor
北京 101111
Quick Overview for Importin 5 抗体 (ABIN8122168)
抗原
See all Importin 5 (IPO5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- IPO5 Antibody
-
特异性
- IPO5 Polyclonal Antibody detects endogenous levels of protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human protein
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000 ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- Importin 5 (IPO5)
-
别名
- IPO5
-
背景
-
Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex.The protein encoded by this gene is a me
Gene Name: IPO5 KPNB3 RANBP5
Protein Name: Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)
-
基因ID
- 3843
-
UniProt
- O00410
-
途径
- Protein targeting to Nucleus
抗原
-