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Huntingtin 抗体 (acLys442)

The 兔 多克隆 anti-Huntingtin antibody is suitable to detect Huntingtin in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8122113
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Huntingtin 抗体 (acLys442) (ABIN8122113)

抗原

See all Huntingtin (HTT) 抗体
Huntingtin (HTT)

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Huntingtin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    acLys442

    原理

    Huntingtin (Acetyl Lys442) Antibody

    特异性

    This antibody detects endogenous levels of Human,Mouse,Rat Huntingtin (Acetyl Lys442)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized peptide derived from human Huntingtin (Acetyl Lys442)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Huntingtin (HTT)

    别名

    Huntingtin

    背景

    Synonyms: Huntingtin (Huntington disease protein; HD protein)

    Background: huntingtin(HTT) Homo sapiens Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal development. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widel

    Gene Name: HTT HD IT15

    Protein Name: Huntingtin (Acetyl Lys442)

    基因ID

    3064

    UniProt

    P42858

    途径

    PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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