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HTRA2 抗体 (pSer142)

The 兔 多克隆 anti-HTRA2 antibody (ABIN8122111) specifically detects HTRA2 in ELISA, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8122111
发货至: 中国
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Quick Overview for HTRA2 抗体 (pSer142) (ABIN8122111)

抗原

See all HTRA2 抗体
HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

适用

  • 130
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人, 小鼠, 大鼠

宿主

  • 115
  • 16
兔

克隆类型

  • 93
  • 38
多克隆

标记

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This HTRA2 antibody is un-conjugated

应用范围

  • 87
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  • 14
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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    pSer142

    原理

    HtrA2 (phospho Ser142) Antibody

    特异性

    Phospho-HtrA2 (S142) Polyclonal Antibody detects endogenous levels of HtrA2 protein only when phosphorylated at S142.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized phospho-peptide around the phosphorylation site of human HtrA2 (phospho Ser142)

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

    别名

    HtrA2

    背景

    Synonyms: HTRA2, OMI, PRSS25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI

    Background: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

    Gene Name: HTRA2

    Protein Name: Serine protease HTRA2 mitochondrial

    基因ID

    27429

    UniProt

    O43464

    途径

    Positive Regulation of Endopeptidase Activity
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