HTRA2 抗体 (pSer142)
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北京 101111
Quick Overview for HTRA2 抗体 (pSer142) (ABIN8122111)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer142
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原理
- HtrA2 (phospho Ser142) Antibody
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特异性
- Phospho-HtrA2 (S142) Polyclonal Antibody detects endogenous levels of HtrA2 protein only when phosphorylated at S142.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized phospho-peptide around the phosphorylation site of human HtrA2 (phospho Ser142)
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- HtrA2
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背景
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Synonyms: HTRA2, OMI, PRSS25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI
Background: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],
Gene Name: HTRA2
Protein Name: Serine protease HTRA2 mitochondrial
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基因ID
- 27429
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UniProt
- O43464
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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