HJURP 抗体 (AA 80-160)
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北京 101111
Quick Overview for HJURP 抗体 (AA 80-160) (ABIN8122100)
抗原
See all HJURP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-160
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原理
- HJURP Antibody
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特异性
- HJURP Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 80-160
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亚型
- IgG
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anti-Holliday Junction Recognition Protein (HJURP) (AA 559-588), (C-Term) antibody
HJURP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB33335 unconjugated
anti-Holliday Junction Recognition Protein (HJURP) (AA 650-700) antibodyHJURP 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Holliday Junction Recognition Protein (HJURP) (C-Term) antibodyHJURP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Holliday Junction Recognition Protein (HJURP) (AA 1-748) antibodyHJURP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Holliday Junction Recognition Protein (HJURP) antibodyHJURP 适用: 人 WB 宿主: 兔 Monoclonal 25GB4675 unconjugated Recombinant Antibody
anti-Holliday Junction Recognition Protein (HJURP) (AA 13-574) antibodyHJURP 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HJURP (Holliday Junction Recognition Protein (HJURP))
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别名
- HJURP
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背景
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Background: function:Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions.,sequence caution:Translated as Arg.,subcellular location:Localizes in centromeres during late telophase and early G1, when CENPA nucleosomes are assembled. Localizes to nucleolus during S phase, nucleolus site being often related to storage.,subunit:Interacts with CENPA (via CATD domain), the interaction is direct and specific for CENPA since it does not interact with H3.1- or H3.3-containing nucleosomes. Interacts with 14-3-3 family members in a phosphorylation-dependent manner. Interacts with MSH5 and NBN.,tissue specificity:According to PubMed:17256767 highly expressed in the thymus with lower levels in the placenta, small intestine, liver, skeletal muscle, and colon. According to PubMed:17823411 highly expressed in testis, and at a relatively lower level in thymus and bone marrow. Significantly overexpressed in many lung cancer samples, compared with normal lung.,
Gene Name: HJURP FAKTS FLEG1 URLC9
Protein Name: Holliday junction recognition protein (14-3-3-associated AKT substrate) (Fetal liver-expressing gene 1 protein) (Up-regulated in lung cancer 9)
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基因ID
- 55355
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UniProt
- Q8NCD3
抗原
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