HNF1A 抗体 (pSer247)
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Quick Overview for HNF1A 抗体 (pSer247) (ABIN8122096)
抗原
See all HNF1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer247
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原理
- HNF1α (Phospho Ser247) Antibody
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特异性
- This antibody detects endogenous levels of Human HNF1α (phospho-Ser247)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human HNF1alpha (Ser247)
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亚型
- IgG
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HNF1A (HNF1 Homeobox A (HNF1A))
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别名
- HNF1alpha
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背景
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Synonyms: Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)
Background: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
Gene Name: HNF1A TCF1
Protein Name: HNF1α (Ser247)
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基因ID
- 6927
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UniProt
- P20823
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途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
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