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HCK 抗体 (pTyr521)

The 兔 多克隆 anti-HCK antibody is suitable to detect HCK in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8121927
发货至: 中国
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Quick Overview for HCK 抗体 (pTyr521) (ABIN8121927)

抗原

See all HCK 抗体
HCK (Hemopoietic Cell Kinase (HCK))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This HCK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pTyr521

    原理

    Hck (phospho Tyr521) Antibody

    特异性

    Phospho-Hck (Y521) Polyclonal Antibody detects endogenous levels of Hck protein only when phosphorylated at Y521.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized phospho-peptide around the phosphorylation site of human Hck (phospho Tyr521)

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HCK (Hemopoietic Cell Kinase (HCK))

    别名

    Hck

    背景

    Synonyms: HCK, Tyrosine-protein kinase HCK, Hematopoietic cell kinase, Hemopoietic cell kinase, p59-HCK/p60-HCK, p59Hck, p61Hck

    Background: The protein encoded byThis gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010],

    Gene Name: HCK

    Protein Name: Tyrosine-protein kinase HCK

    基因ID

    3055

    UniProt

    P08631

    途径

    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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