HSPB8 抗体
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北京 101111
Quick Overview for HSPB8 抗体 (ABIN8121889)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Crystallin-αC Antibody
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特异性
- The antibody detects endogenous Crystallin-αC protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Recombinant Protein of Crystallin-alphaC
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亚型
- IgG
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应用备注
- WB 1:500-1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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别名
- Crystallin-alphaC
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背景
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Synonyms: HSPB8, CRYAC, E2IG1, HSP22, PP1629, Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22
Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],
Gene Name: HSPB8
Protein Name: Heat shock protein beta-8
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基因ID
- 26353
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UniProt
- Q9UJY1
抗原
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