CADM1 抗体 (PE-Cy5)
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- 抗原 See all CADM1 抗体
- CADM1 (Cell Adhesion Molecule 1 (CADM1))
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CADM1 antibody is conjugated to PE-Cy5
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CADM1/TSLC1
- 亚型
- IgG
- Top Product
- Discover our top product CADM1 Primary Antibody
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anti-Cell Adhesion Molecule 1 (CADM1) (AA 151-250) antibody
CADM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 365-442) antibodyCADM1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (Internal Region) antibodyCADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 65-160) antibodyCADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibodyCADM1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 45-344) antibodyCADM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibodyCADM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 27-292) antibodyCADM1 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 45-344) antibodyCADM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 66-94), (N-Term) antibodyCADM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB22685 unconjugated
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- 应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CADM1 (Cell Adhesion Molecule 1 (CADM1))
- 别名
- TSLC1 (CADM1 产品)
- 背景
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Synonyms: BL2, ST17, IGSF4, NECL2, RA175, TSLC1, IGSF4A, Necl-2, SYNCAM, sgIGSF, sTSLC-1, synCAM1, Cell adhesion molecule 1, Immunoglobulin superfamily member 4, Nectin-like protein 2, Spermatogenic immunoglobulin superfamily, Synaptic cell adhesion molecule, Tumor suppressor in lung cancer 1, TSLC-1, CADM1
Background: Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
- 分子量
- 49kDa
- 基因ID
- 23705
- UniProt
- Q9BY67
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
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