GP1BB 抗体 (AA 90-150)
Our Local Distributor
北京 101111
Quick Overview for GP1BB 抗体 (AA 90-150) (ABIN8121769)
抗原
See all GP1BB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 90-150
-
原理
- CD42c Antibody
-
特异性
- The antibody detects endogenous CD42c
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthetic peptide from human protein at AA range: 90-150
-
亚型
- IgG
-
-
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 52-164) antibody
GP1BB 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 56-118) antibodyGP1BB 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) antibodyGP1BB 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 27-147) antibodyGP1BB 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (AA 53-176) antibodyGP1BB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB) (Internal Region) antibodyGP1BB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))
-
别名
- CD42c
-
背景
-
Synonyms: Platelet glycoprotein Ib beta chain (GP-Ib beta, GPIb-beta, GPIbB, Antigen CD42b-beta, CD antigen CD42c)
Background: Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described, however, t
Gene Name: GP1BB
Protein Name: Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c)
-
基因ID
- 2812
-
UniProt
- P13224
抗原
-
