GSTM3 抗体 (AA 1-51)
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北京 101111
Quick Overview for GSTM3 抗体 (AA 1-51) (ABIN8121721)
抗原
See all GSTM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-51
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原理
- GSTM3 Antibody
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特异性
- This antibody detects endogenous levels of GSTM3 at Human
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human GSTM3 AA range: 1-51
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
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别名
- GSTM3
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背景
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Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008],
Gene Name: GSTM3 GST5
Protein Name: GSTM3
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基因ID
- 2947
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UniProt
- P21266
抗原
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