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GPX3 抗体

This 兔 多克隆 antibody specifically detects GPX3 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8121710
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GPX3 抗体 (ABIN8121710)

抗原

See all GPX3 抗体
GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

适用

  • 35
  • 33
  • 20
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 51
  • 3
  • 1
兔

克隆类型

  • 54
  • 1
多克隆

标记

  • 26
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GPX3 antibody is un-conjugated

应用范围

  • 55
  • 21
  • 13
  • 13
  • 12
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    GPX3 Antibody

    特异性

    GPX3 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

    别名

    GPX3

    背景

    Background: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is secreted, and is abundantly found in plasma. Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies, including thyroid cancer, hepatocellular carcinoma and chronic myeloid leukemia. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designa

    Gene Name: GPX3 GPXP

    Protein Name: Glutathione peroxidase 3 (GPx-3) (GSHPx-3) (EC 1.11.1.9) (Extracellular glutathione peroxidase) (Plasma glutathione peroxidase) (GPx-P) (GSHPx-P)

    基因ID

    2878

    UniProt

    P22352

    途径

    Thyroid Hormone Synthesis
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