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Glutathione Peroxidase 2 抗体 (AA 113-163)

The 兔 多克隆 anti-Glutathione Peroxidase 2 antibody (ABIN8121709) specifically detects Glutathione Peroxidase 2 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8121709
发货至: 中国
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Quick Overview for Glutathione Peroxidase 2 抗体 (AA 113-163) (ABIN8121709)

抗原

See all Glutathione Peroxidase 2 (GPX2) 抗体
Glutathione Peroxidase 2 (GPX2)

适用

  • 27
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 26
  • 1
兔

克隆类型

  • 16
  • 11
多克隆

标记

  • 14
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Glutathione Peroxidase 2 antibody is un-conjugated

应用范围

  • 20
  • 17
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 113-163

    原理

    GPX2 Antibody

    特异性

    This antibody detects endogenous levels of GPX2 at Human/Mouse/Rat

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human GPX2 AA range: 113-163

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Glutathione Peroxidase 2 (GPX2)

    别名

    GPX2

    背景

    Background: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016],

    Gene Name: GPX2

    Protein Name: GPX2

    基因ID

    2877

    UniProt

    P18283

    途径

    Thyroid Hormone Synthesis
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