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Glutathione Peroxidase 1 抗体

The 兔 多克隆 anti-Glutathione Peroxidase 1 antibody is suitable to detect Glutathione Peroxidase 1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8121708
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Glutathione Peroxidase 1 抗体 (ABIN8121708)

抗原

See all Glutathione Peroxidase 1 (GPX1) 抗体
Glutathione Peroxidase 1 (GPX1)

适用

  • 113
  • 78
  • 77
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 95
  • 19
  • 4
  • 2
兔

克隆类型

  • 73
  • 47
多克隆

标记

  • 47
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  • 5
  • 5
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  • 4
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  • 4
  • 4
  • 4
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  • 3
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  • 1
This Glutathione Peroxidase 1 antibody is un-conjugated

应用范围

  • 72
  • 54
  • 45
  • 39
  • 32
  • 29
  • 12
  • 10
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    GPX1 Antibody

    特异性

    GPX1 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Glutathione Peroxidase 1 (GPX1)

    别名

    GPX1

    背景

    Background: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA cod

    Gene Name: GPX1

    Protein Name: Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase)

    基因ID

    2876

    UniProt

    P07203

    途径

    Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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