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GLN1 抗体

The 兔 单克隆 anti-GLN1 antibody is suitable to detect GLN1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC, IF, IP 和 ELISA.
产品编号 ABIN8121699
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GLN1 抗体 (ABIN8121699)

抗原

See all GLN1 抗体
GLN1 (Glutamine Synthetase (GLN1))

适用

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人, 大鼠, 小鼠

宿主

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兔

克隆类型

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单克隆

标记

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This GLN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA

克隆位点

AB1655
  • 原理

    Glutamine Synthetase Rabbit mAb

    特异性

    This antibody detects endogenous levels of Glutamine Synthetase protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:1000-1:5000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    GLN1 (Glutamine Synthetase (GLN1))

    别名

    Glutamine Synthetase

    背景

    Synonyms: GLUL, GLNS, Glutamine synthetase, GS, Glutamate decarboxylase, Glutamate-- ammonia ligase

    Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

    Gene Name: >>Arginine biosynthesis, >>Alanine, aspartate and glutamate metabolism, >>Glyoxylate and dicarboxylate metabolism, >>Nitrogen metabolism, >>Metabolic pathways, >>Biosynthesis of amino acids, >>Necroptosis, >>Glutamatergic synapse, >>GABAergic synapse

    Protein Name: Glutamine Synthetase

    基因ID

    2752

    UniProt

    P15104

    途径

    Positive Regulation of Peptide Hormone Secretion
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