GLUL 抗体 (AA 400-500)
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北京 101111
Quick Overview for GLUL 抗体 (AA 400-500) (ABIN8121691)
抗原
See all GLUL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 400-500
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原理
- Gl Syn/Glutamine Synthetase mouse mAb
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特异性
- This antibody detects endogenous levels of Gl Syn/Glutamine Synthetase protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Beta Tubulin protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- GLUL (Glutamate-Ammonia Ligase (GLUL))
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别名
- Gl Syn/Glutamine Synthetase
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背景
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Synonyms: GLUL,GLNS,Glutamine synthetase,GS,Glutamate decarboxylase,Glutamate-- ammonia ligase
Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
Gene Name: GLUL
Protein Name: Gl Syn/Glutamine Synthetase
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基因ID
- 2752
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UniProt
- P15104
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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