GRIA2 抗体 (pTyr876)
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北京 101111
Quick Overview for GRIA2 抗体 (pTyr876) (ABIN8121685)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr876
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原理
- GluR-2 (Phospho Tyr876) Antibody
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特异性
- This antibody detects endogenous phospho levels of GluR-2 (Phospho-Tyr876) at Human:Y876, Mouse:Y876, Rat:Y876
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human GluR-2 (Phospho-Tyr876)
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody
GRIA2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7G6 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 35-175) antibodyGRIA2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A7A3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 834-883), (C-Term), (Cytosolic) antibodyKO Validated GRIA2 适用: 大鼠 WB, IHC, ELISA, ICC, IP, EM 宿主: 小鼠 Monoclonal L21-32 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 175-430) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 413-527) antibodyGRIA2 适用: 人 IHC, IF, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Extracellular), (N-Term) antibodyKO Validated GRIA2 适用: 大鼠 WB, IHC, IF, IP, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Extracellular), (N-Term) antibodyGRIA2 适用: 大鼠 WB, IF, IC, LCI 宿主: 豚鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 151-250) antibodyGRIA2 适用: 人 WB, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-200, WB 1:500-2000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- GluR-2
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背景
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Synonyms: Glutamate receptor 2 (GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2)
Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants enco
Gene Name: GRIA2 GLUR2
Protein Name: GluR-2 (Phospho-Tyr876)
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基因ID
- 2891
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UniProt
- P42262
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途径
- PI3K-Akt Signaling
抗原
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