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GIT2 抗体 (pTyr392)

This 兔 多克隆 antibody specifically detects GIT2 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8121560
发货至: 中国
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Quick Overview for GIT2 抗体 (pTyr392) (ABIN8121560)

抗原

See all GIT2 抗体
GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This GIT2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pTyr392

    原理

    GIT2 (Phospho Tyr392) Antibody

    特异性

    This antibody detects endogenous levels of Human GIT2 (phospho-Tyr392)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized phosho peptide around human GIT2 (Tyr392)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

    别名

    GIT2

    背景

    Synonyms: ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)

    Background: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G

    Gene Name: GIT2 KIAA0148

    Protein Name: GIT2 (Tyr392)

    基因ID

    9815

    UniProt

    Q14161

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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