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Filamin A 抗体

This 兔 单克隆 antibody specifically detects Filamin A in WB, IHC, ELISA, IF 和 IP. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8121458
发货至: 中国
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Quick Overview for Filamin A 抗体 (ABIN8121458)

抗原

See all Filamin A (FLNA) 抗体
Filamin A (FLNA) (Filamin A, alpha (FLNA))

适用

  • 142
  • 54
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  • 1
人, 小鼠, 大鼠

宿主

  • 119
  • 22
  • 1
兔

克隆类型

  • 98
  • 44
单克隆

标记

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This Filamin A antibody is un-conjugated

应用范围

  • 88
  • 61
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  • 8
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

AB1900
  • 原理

    Filamin A Rabbit mAb

    特异性

    This antibody detects endogenous levels of Filamin A protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:1000-1:5000 | IHC, 1:4000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    Filamin A (FLNA) (Filamin A, alpha (FLNA))

    别名

    Filamin A

    背景

    Synonyms: FLNA, FLN, FLN1, Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin

    Background: filamin A (FLNA) Homo sapiens    The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4) , otopalatodigital syndromes (OPD1, OPD2) , frontometaphyseal dysplasia (FMD) , Melnick-Needles syndrome (MNS) , and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

    Gene Name: FLNA

    Protein Name: Filamin A

    基因ID

    2316

    UniProt

    P21333

    途径

    TCR Signaling, Maintenance of Protein Location
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